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Screenshot of a Focus Online newspaper article titled "Alarming Studies: High Fluoride Content in Drinking Water Said to Significantly Reduce Children's IQ" on a dark blue background; to underline the headline "Always Convinced — With BioHAP Instead of Fluoride"Screenshot of a Focus Online newspaper article titled "Alarming Studies: High Fluoride Content in Drinking Water Said to Significantly Reduce Children's IQ" on a dark blue background; to underline the headline "Always Convinced — With BioHAP Instead of Fluoride"

Always Convinced — With BioHAP Instead of Fluoride

zm online: FDA Warns: Fluoride Tablets for Children Are Risky

focus: High Fluoride Content in Drinking Water Said to Significantly Reduce IQ in Children

New York Times: The Anti-Fluoride Movement Is Breaking Into the Mainstream

CNN: Fluoride During Pregnancy May Harm Children

The Guardian: US Authorities Want to Minimize Fluorosis Risks From Too Much Fluoride

KAREX: BioHAP – The Next Generation of Tooth Protection

Fluoride has long been used in cavity prevention, but it can carry risks — especially for children. KAREX is therefore taking a new approach: We rely on BioHAP, the scientifically proven active ingredient that prevents cavities just as effectively as fluoride — but without the risks. This makes KAREX the modern, safe choice for tooth protection for everyone — from the very first tooth.

Products: Ideal for Children: Cavity Protection Without Risk

Zwei Tuben KINDER KAREX Zahnpasta, Aufschrift: „Zahnpasta mit BioHAP ohne Fluorid. Biomimetischer Hydroxylapatit“.

KINDER KAREX toothpaste

2-pack

€8.98100 ml (€89.80 / 1 l) • incl. VAT, plus shipping
Zwei Tuben JUNIOR KAREX Zahnpasta, Aufschrift: „Zahnpasta mit BioHAP ohne Fluorid. Biomimetischer Hydroxylapatit“.

JUNIOR KAREX toothpaste

2-pack

€9.98130 ml (€76.77 / 1 l) • incl. VAT, plus shipping
Zwei Tuben KAREX Zahnpasta, „Ohne Fluorid“ und „Wirksamer Kariesschutz mit BioHAP statt Fluorid. Biomimetischer Hydroxylapatit“.

KAREX toothpaste

2-pack

€11.98150 ml (€79.87 / 1 l) • incl. VAT, plus shipping
Zwei Tuben BABY KAREX Zahnpasta, Aufschrift: „Zahnpasta mit BioHAP ohne Fluorid. Biomimetischer Hydroxylapatit“.

BABY KAREX toothpaste

2-pack

€9.98100 ml (€99.80 / 1 l) • incl. VAT, plus shipping
Zwei Tuben MAMA KAREX Zahnpasta, Aufschrift: „Zahnpasta mit BioHAP ohne Fluorid. Biomimetischer Hydroxylapatit“.

MAMA KAREX toothpaste

2-pack

€11.98150 ml (€79.87 / 1 l) • incl. VAT, plus shipping
Zwei Tuben KAREX Zahnschutzgel, Aufschrift: „Zahnschutzgel mit BioHAP ohne Fluorid. Biomimetischer Hydroxylapatit“.

KAREX tooth protection gel

2-pack

€17.98100 ml (€179.80 / 1 l) • incl. VAT, plus shipping

Find your KAREX

The Direct Comparison

A table comparing BioHAP and fluoride in the categories of cavity protection, swallowing, fluorosis protection, and suitability for chalky teeth (MIH). BioHAP offers advantages in all areas, while fluoride only matches BioHAP in cavity protection, but is inferior in all other categories.

Fluoride Risks: Fluoride Risks in Focus

  • Fluorosis

  • IQ Reduction

  • Risks During Pregnancy

  • Alzheimer's disease

Background Information on Fluoride Risks

BioHAP: Modern Dental Care for Children: With KAREX and BioHAP

What kind of active ingredient is BioHAP?

BioHAP stands for biomimetic Hydroxyapatite — the main component of our natural tooth enamel.

BioHAP helps protect against cavities and remineralize damaged tooth enamel.

Recommended: Canadian Dental Association Confirms Efficacy of BioHAP Against Cavities

Logo der kanadischen Zahnärztekammer (Canadian Dental Association) als Beleg dafür, dass KAREX die einige fluoridfreie Zahnpasta mit Hydroxylapatit ist, die in Kanada von der Health Canada zur Vorbeugung von Karies zugelassen ist

Clinically confirmed: KINDER KAREX Toothpaste is the first and only fluoride-free toothpaste with Hydroxyapatite to be approved in Canada by the health authorities (Health Canada) as an anti-cavity toothpaste. It is therefore a so-called "Natural Health Product." This product status can only be achieved when scientifically sound clinical data on efficacy and safety are available. In addition, the efficacy of the toothpaste with Hydroxyapatite has been confirmed by the Canadian Dental Association (CDA).

The Benefits of BioHAP

  • Logos of the Max Planck Society, the Fraunhofer Institute, the Public Health Department of the City of Braunschweig, and Charité – Universitätsmedizin Berlin are arranged on a light blue background, symbolizing some of the research institutions that have published studies on Hydroxyapatite and BioHAP in oral care.

    Cavity protection proven by studies

    Numerous scientific publications confirm the effect of Hydroxyapatite in oral care. BioHAP is at least as effective as fluoride in cavity prevention.

  • A mother is sitting in the bathroom with her baby on her lap; the baby is holding a baby toothbrush in one hand and an open tube of BABY KAREX with BioHAP instead of fluoride in the other, symbolizing the appropriate oral care for babies.

    Safe use

    Small children usually cannot spit out toothpaste properly yet and swallow a large portion of it – with BioHAP this is harmless. No strict dosage requirements as with fluoride-containing toothpastes.

  • A girl in a blue-and-white striped top smiles at the camera; white spots can be seen on her front teeth, which are signs of fluorosis, an enamel defect caused by excessive fluoride intake.

    Reduced risk of fluorosis

    The permanent damage to tooth enamel (fluorosis) is caused by an overdose of fluoride. KAREX is effective without fluoride. Toothpaste with BioHAP can be swallowed without hesitation.

ᑎ Fluoride Action Network (FAN), 2015. Submission to the National Toxicology Program: Review of fluoride for non-cancer health outcomes, including developmental neurotoxicity and endocrine disruption.

ᐳ Bai, R., Huang, Y., Wang, F., & Guo, J., 2020. Associations of fluoride exposure with sex steroid hormones among U.S. children and adolescents, NHANES 2013–2016. Environmental Pollution, 260, p.114003. doi: 10.1016/j.envpol.2020.114003.

ᑐ National Institute of Dental and Cranofacial Research: The Story of Fluoridation

ᕒ Pawinska, M., Paszynska, E., Amaechi, B. T., Meyer, F., Enax, J., & Limeback, H. (2024): Clinical evidence of caries prevention by hydroxyapatite: An updated systematic review and meta-analysis. Journal of Dentistry, 151