Questions and answers about Karex

Our enamel is made up almost exclusively of hydroxyapatite. Therefore, hydroxyapatite is used as a biomimetic agent in oral care. Many studies prove the benefit of hydroxyapatite in oral care/prophylaxis.

Yes, Karex protects against caries. The efficacy was confirmed in a clinical study. It shows that the hydroxyapatite toothpaste is just as effective in preventing caries as a fluoride toothpaste with amine fluoride and tin fluoride. There are also in vivo studies that describe the effective removal of plaque, gum protection as well as the formation of a protective layer when hydroxyapatite oral care preparations are used.

Yes, Karex also offer protection with reduced saliva. Traditional oral care products improve the natural remineralisation from saliva, but cannot be fully effective if the flow of saliva is reduced. Hydroxyapatite, the active ingredient in Karex, is already present in mineral form and does not have to be formed from the saliva through remineralisation processes.

Yes, many publications confirm the efficacy. In addition to laboratory studies (in vitro), these include studies with test specimens under oral cavity conditions (in situ) as well as clinical studies on patients (in vivo) in particular. Literature

Harks, I. et al. Impact of the daily use of a microcrystal hydroxyapatite dentifrice on de novo plaque formation and clinical/microbiological parameters of periodontal health. A randomized trial. PloS one 11, e0160142 (2016).

Lelli, M. et al. Remineralization and repair of enamel surface by biomimetic Zn-carbonate hydroxyapatite containing toothpaste: a comparative in vivo study. Front. Physiol. 5, 333 (2014).

Orsini, G. et al. A double-blind randomized-controlled trial comparing the desensitizing efficacy of a new dentifrice containing carbonate/hydroxyapatite nanocrystals and a sodium fluoride/potassium nitrate dentifrice. J. Clin. Periodontol. 37, 510-517 (2010).

Kani, K. et al. Effect of apatite-containing dentifrices on dental caries in school children. J. Dent. Health 19, 104-109 (1989).

No, Karex does not contain fluoride. Karex contains the biomimetic active ingredient hydroxyapatite, which prevents caries. 

The aroma contains menthol and eucalyptol. Please take this into account if you are undergoing homeopathic treatment.

Karex does not contain gluten.

Karex toothpaste and mouthwash have been developed for daily use, including on crowns or dentures.

No, Karex does not contain nanoparticles.

Karex does not contain any animal substances. Therefore, the Karex product range is vegan.