Clinical anti-caries study
The percentage of people with no caries was larger in the group that cleaned their teeth with Karex than in the fluoride group.
The carious lesions were detected according to the most advanced standards (International Caries Detection and Assessment System / ICDAS). 1
The study was conducted on patients with a high risk of caries. All patients wore fixed braces. People with fixed braces can develop initial carious lesions within a very short period of time, despite brushing. 2-4 Removing plaque from around the braces is generally extremely difficult.
This double-blind, randomised clinical study was conducted at several German university hospitals.
It was presented at a press symposium at the world's largest dental show in Cologne in March 2017.
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Figure: No differences in the development of caries could be detected between the use of a toothpaste with fluoride (amine and tin fluoride) and the Karex toothpaste. The average percentage of patients without caries was actually slightly lower in the Karex group.
1 Ismail, A. I. et al. The International Caries Detection and Assessment System (ICDAS): an integrated system for measuring dental caries. Community dentistry and oral epidemiology 35, 170-178, doi:10.1111/j.1600-0528.2007.00347.x (2007).
2 Khoroushi, M. & Kachuie, M. Prevention and Treatment of White Spot Lesions in Orthodontic Patients. Contemporary Clinical Dentistry 8, 11-19, doi:10.4103/ccd.ccd_216_17 (2017).
3 Chapman, J. A., Roberts, W. E., Eckert, G. J., Kula, K. S. & Gonzalez-Cabezas, C. Risk factors for incidence and severity of white spot lesions during treatment with fixed orthodontic appliances. American journal of orthodontics and dentofacial orthopedics : official publication of the American Association of Orthodontists, its constituent societies, and the American Board of Orthodontics 138, 188-194, doi:10.1016/j.ajodo.2008.10.019 (2010).
4 Enaia, M., Bock, N. & Ruf, S. White-spot lesions during multibracket appliance treatment: A challenge for clinical excellence. American journal of orthodontics and dentofacial orthopedics : official publication of the American Association of Orthodontists, its constituent societies, and the American Board of Orthodontics 140, e17-24, doi:10.1016/j.ajodo.2010.12.016 (2011).