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    Dental care for babies and mothers: A hand holds one tube each of BABY KAREX and MAMA KAREX as well as a pink toothbrush, as a symbol of the right toothpaste for babies and toothpaste from pregnancy onwards.Dental care for babies and mothers: A hand holds one tube each of BABY KAREX and MAMA KAREX as well as a pink toothbrush, as a symbol of the right toothpaste for babies and toothpaste from pregnancy onwards.

    Toothpaste for Baby & Mom with BioHAP Instead of Fluoride

    BabyBaby: Into the world of brushing teeth with BABY KAREX

    • Clinically confirmed cavity protection for the first teeth

    • Safe if swallowed

    • Flavor-free and yet pleasant in taste

    MamaMama: KAREX for mothers

    • Effective cavity protection clinically confirmed

    • Also suitable for sensitive teeth & sensitive gums during pregnancy

    • Remineralizes teeth & minimizes bacterial adhesion

    StudiesStudies: BioHAP is just as effective as fluoride in cavity prevention

    • Clinical studyClinical study: 291

      studies were identified that investigated BioHAP in the context of dental care.

    • Clinical studyClinical study: 90 %

      caries-free patients while using toothpaste with BioHAP.

    • Clinical studyClinical study: 100 %

      of parents use too much fluoride-containing toothpaste for their children.

    • Clinical studyClinical study: 39.3 %

      of parents are not informed about the conditions of use and warnings of fluoride toothpastes.

    • Further studies & research findings

    GuideGuide: Dental care for babies & mothers in focus

    • Brushing baby’s teeth: A mother has her baby on her lap in the bathroom; the baby is holding a baby toothbrush in one hand and an open tube of BABY KAREX with BioHAP instead of fluoride in the other, symbolizing appropriate dental care for babies

      When should you start brushing your baby’s teeth?

    • Toothache during pregnancy: A pregnant woman is holding a toothbrush in front of her baby bump, symbolizing proper dental care during pregnancy

      Pregnancy and toothache: tips for you

    • Teething baby: A mother has her baby on her lap; she is holding a baby toothbrush in one hand and wants to brush her baby’s teeth with it, symbolizing dental care from the very first tooth

      Immediate relief during teething: How to help your baby

    BioHAP benefitsBioHAP benefits: What exactly is BioHAP?

    KAREX – consciously with BioHAP instead of fluoride

    • Free shipping from €15

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    • BioHAP instead of fluoride
      • Fluoride Risks
        Fluoride Risks
        • What is BioHAP?
          What is BioHAP?
        • Baby & Mama
          • Products
            • BABY KAREX toothpaste
            • MAMA KAREX toothpaste
            • KAREX toothpaste
            • View all
          • Dental care tips
            • Teething in babies: Help & tips when babies are getting their teeth
            • The first dental care: From when should you start brushing your baby's teeth?
            • Tips for toothache during pregnancy
        • Kids
          • Products
            • KINDER KAREX toothpaste
            • KAREX tooth protection gel
            • View all
          • Tips for healthy baby teeth
            • Cavities in children: Tips for prevention and proper dental care
            • Fluorosis: What are the white spots on the teeth?
            • More guides
        • Junior
          • Products
            • JUNIOR KAREX toothpaste
            • KAREX tooth protection gel
            • View all
          • Tips for permanent teeth
            • Tooth loss in children: A closer look at the mixed dentition
            • Chalk teeth in children: Symptoms, causes, and treatment
            • More guides
        • Research
          • Research at Dr. Wolff
            Research at Dr. Wolff
            • BioHAP Studies
              BioHAP Studies
              • Benefits of fluoride-free toothpastes with BioHAP
                Benefits of fluoride-free toothpastes with BioHAP
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                About KAREX
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                FAQFAQ: Answers to your questions

                The use of fluoride in toothpaste is particularly controversial for children under 6 years of age. Children in particular swallow a large portion of the toothpaste. Due to the intake of additional sources of fluoride (vitamin D supplements with fluoride, fluoridated salt, etc.), the risk of fluorosis (discoloration of the teeth caused by increased fluoride intake) increases significantly. For example, the German Federal Institute for Risk Assessment points out that if a children’s toothpaste with 500 ppm fluoride is swallowed, just as much fluoride is ingested as, for instance, through fluoridated salt. According to the new recommendations, the amount of swallowed fluoride can therefore double. The risk of fluorosis is significantly higher with toothpastes that have a higher fluoride content (from 1000 ppm).

                BABY KAREX Toothpaste relies on the tooth-related active ingredient Hydroxyapatite. When swallowed, it is simply dissolved in the stomach.
                Numerous studies confirm its effectiveness: Hydroxyapatite repairs enamel with every brushing, reduces bacterial adhesion, and thus provides effective protection against cavities.

                Our tooth enamel consists almost entirely of Hydroxyapatite. That is why BioHAP (biomimetic Hydroxyapatite) is used as an active ingredient in oral care. The highly concentrated active ingredient also serves as a source of calcium and protects our teeth against bacterial acids. Numerous studies confirm the benefits of Hydroxyapatite in the field of oral care and prevention.

                Yes, BioHAP protects just as effectively as fluoride against cavities. BioHAP forms a protective layer on the tooth surface that prevents bacteria from adhering to the tooth and thus helps prevent cavities and gum inflammation. In addition, BioHAP releases calcium during acid attacks, which protects the teeth.

                In contrast to many other fluoride-free toothpastes, KAREX uses Hydroxyapatite (BioHAP) as its active ingredient. This is the substance our teeth are made of. BioHAP protects at least as effectively against cavities as fluoride – without the risks of overdosing.

                KAREX is “Made in Germany” and is developed and distributed by the Dr. Wolff Group, a fourth-generation family-owned company based in Bielefeld.

                You probably already know one of our other strong brands such as Alpecin, ALCINA, Plantur, Linola, Bioniq® or V-san. You can find out more about us at .

                Numerous publications confirm the effectiveness of BioHAP in dental care. These include not only laboratory studies (in vitro) but also studies with test specimens under oral cavity conditions (in situ), as well as, in particular, clinical studies on patients (in vivo).
                For more information, feel free to read the German short summary or the original study. You can get an overview of the large number of studies on Hydroxyapatite as an active ingredient in dental care by browsing (usable without registration).

                View all FAQs

                ▲ Limeback, H., Enax, J. & Meyer, F. (2021): Biomimetic hydroxyapatite and caries prevention: a systematic review and meta-analysis. Can J Dent Hyg. 2021 Oct 1;55(3):148–159.

                ◓ Amaechi, B.T., AbdulAzees, P.A., Okoye, L.O. et al. (2020) Comparison of hydroxyapatite and fluoride oral care gels for remineralization of initial caries: a pH-cycling study. BDJ Open 6, 98-159

                △ Sudradjat, H., Meyer, F., Fandrich, P. et al. (2024): Doses of fluoride toothpaste for children up to 24 months. BDJ Open 10, 7

                Discover the new MAMA & BABY KAREX Toothpaste with BioHAP! Specially developed for the needs of mothers and their babies, it provides optimal dental care and strengthens tooth enamel in a natural way. Protect your teeth and your baby's teeth with the gentle and effective care formula of BioHAP.

                Our articles inform you about dental problems during pregnancy and show you how you can prevent them. You will also receive valuable tips on how to optimally manage your baby's dental care.

                Start dental care from the very first tooth! Find out now how you can ensure healthy teeth from the beginning and lay the foundation for lifelong oral health.

                Toothache during pregnancy? Find out why this happens and how you can protect your teeth. Discover the best tips now!

                Actively support your baby during teething! Discover the best tips now to relieve pain and make the process easier. Your baby will thank you!

                BioHAP is hydroxyapatite – the substance our teeth are made of. But BioHAP also stands for effective cavity protection without risk: the alternative for children and for everyone who does not want fluoride in their toothpaste.

                BioHAP is just as effective as fluoride in caries prevention.▲

                The gel with BioHAP was just as effective in remineralizing caries as the fluoride-containing adult toothpaste (88% caries-free patients).◓

                The results of the study showed that the average amounts of toothpaste used by parents were significantly higher than the rice grain-sized recommended dose.
                For toothpaste with BioHAP, there are no dosage restrictions.

                The study shows that parents overdose fluoride-containing toothpastes. This leads to increased fluoride intake, which can result in fluorosis.△

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                For the sake of better readability, the simultaneous use of the masculine, feminine, and diverse (m/f/d) gender forms is omitted. All references to persons apply equally to all genders.

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                Zwei Tuben BABY KAREX Zahnpasta, Aufschrift: „Zahnpasta mit BioHAP ohne Fluorid. Biomimetischer Hydroxylapatit“.

                BABY KAREX toothpaste

                2-pack

                €9.98100 ml (€99.80 / 1 l) • incl. VAT, plus shipping
                Zwei Tuben KAREX Zahnschutzgel, Aufschrift: „Zahnschutzgel mit BioHAP ohne Fluorid. Biomimetischer Hydroxylapatit“.

                KAREX tooth protection gel

                2-pack

                5 / 5 (12)
                €17.98100 ml (€179.80 / 1 l) • incl. VAT, plus shipping
                All KAREX Products
                Zwei Tuben MAMA KAREX Zahnpasta, Aufschrift: „Zahnpasta mit BioHAP ohne Fluorid. Biomimetischer Hydroxylapatit“.

                MAMA KAREX toothpaste

                2-pack

                5 / 5 (5)
                €11.98150 ml (€79.87 / 1 l) • incl. VAT, plus shipping
                Zwei Tuben KAREX Zahnpasta, „Ohne Fluorid“ und „Wirksamer Kariesschutz mit BioHAP statt Fluorid. Biomimetischer Hydroxylapatit“.

                KAREX toothpaste

                2-pack

                5 / 5 (40)
                €11.98150 ml (€79.87 / 1 l) • incl. VAT, plus shipping
                All KAREX Products