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    Vorderseite der Karex Baby Zahnpasta-Verpackung (50 ml) mit passender Tube im Vordergrund. Beide zeigen das „BABY KAREX“-Logo sowie den Text „Zahnpasta mit BioHAP® ohne Fluorid“ und „Biomimetischer Hydroxylapatit“. Pluspunkte auf der Verpackung: „Kariesschutz für erste Zähnchen“ und „Reduziert das Fluorose-Risiko“. Made in Germany.
    Rückseite der Karex Baby Zahnpasta-Verpackung, 50 ml, in Weiß und Türkis. Oben das „BABY KAREX“-Logo mit „Zahnpasta“-Schriftzug. Im türkisfarbenen Textfeld Produktbeschreibung: Karex Baby Zahnpasta bietet Kariesschutz mit BioHAP (biomimetischer Hydroxylapatit), speziell für die ersten Zähne, ohne Fluorid. Vorteile: remineralisiert die Zähne, minimiert Bakterienanlagerung, fluoridfreie Rezeptur senkt das Fluorose-Risiko, mildes Aroma für Babys.
    Seitenansicht der Karex Baby Zahnpasta-Verpackung, 50 ml, in Weiß und Türkis. Oben das „BABY KAREX“-Logo mit „Zahnpasta“-Schriftzug. Im türkisfarbenen Feld drei Symbole: ohne Fluorid, ohne Titandioxid, ohne Natriumlaurylsulfat. Darunter die Inhaltsliste (Aqua, Hydrated Silica, Glycerin, Sorbitol, Hydroxyapatite, Xylitol, u.a.). Hersteller: Dr. Kurt Wolff, Bielefeld, Deutschland.
    Seitenansicht der Karex Baby Zahnpasta-Verpackung, 50 ml, in Weiß und Türkis. Oben das „BABY KAREX“-Logo mit „Zahnpasta“-Schriftzug. Im türkisfarbenen Bereich der Hinweis „Fluoridfreier Kariesschutz“ sowie Text mit Verweis auf Informationen und Studien zur Wirksamkeit von BioHAP (biomimetischer Hydroxylapatit) und fluoridfreier Zahnpasta auf www.karex.de
    Rückseite der Karex Baby Zahnpasta-Tube, 50 ml, mit blauem Text. Beschreibung: Karex Baby Zahnpasta bietet wirksamen Kariesschutz mit BioHAP (biomimetischer Hydroxylapatit), fluoridfrei, speziell für die ersten Zähnchen. Vorteile: Remineralisiert die Zähne, minimiert Bakterienanlagerung, fluoridfreie Rezeptur senkt das Fluorose-Risiko, mildes Aroma für Babys. Hersteller: Dr. Kurt Wolff, Bielefeld, Deutschland.
    Zwei Tuben BABY KAREX Zahnpasta, Aufschrift: „Zahnpasta mit BioHAP ohne Fluorid. Biomimetischer Hydroxylapatit“.
    Drei Tuben BABY KAREX Zahnpasta, Aufschrift: „Zahnpasta mit BioHAP ohne Fluorid. Biomimetischer Hydroxylapatit“.
    Vier Tuben BABY KAREX Zahnpasta, Aufschrift: „Zahnpasta mit BioHAP ohne Fluorid. Biomimetischer Hydroxylapatit“.

    BABY KAREX toothpaste

    Cavity protection from the first tooth

    • Effective cavity protection
    • Aroma-free – mild and pleasant taste
    • Only the most essential ingredients – free from fluoride and surfactants
    • Harmless if swallowed
    €9.98100 ml (€99.80 / 1 l) • incl. VAT, plus shipping

    Delivery options

    available

    Delivery time: 2–4 working days

    Free shipping from €15

    Aqua, Glycerin, Sorbitol, Hydrated Silica, Hydroxyapatite, Propanediol, Calcium Lactate, Cellulose Gum, Silica, Xylitol, Sodium Saccharin, Potassium Sorbate, Sodium Benzoate.
    • Free shipping from €15

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    • BioHAP instead of fluoride
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    Logo KAREX
    Logo KAREX
    • BioHAP instead of fluoride
      • Fluoride Risks
        Fluoride Risks
        • What is BioHAP?
          What is BioHAP?
        • Baby & Mama
          • Products
            • BABY KAREX toothpaste
            • MAMA KAREX toothpaste
            • KAREX toothpaste
            • View all
          • Dental care tips
            • Teething in babies: Help & tips when babies are getting their teeth
            • The first dental care: From when should you start brushing your baby's teeth?
            • Tips for toothache during pregnancy
        • Kids
          • Products
            • KINDER KAREX toothpaste
            • KAREX tooth protection gel
            • View all
          • Tips for healthy baby teeth
            • Cavities in children: Tips for prevention and proper dental care
            • Fluorosis: What are the white spots on the teeth?
            • More guides
        • Junior
          • Products
            • JUNIOR KAREX toothpaste
            • KAREX tooth protection gel
            • View all
          • Tips for permanent teeth
            • Tooth loss in children: A closer look at the mixed dentition
            • Chalk teeth in children: Symptoms, causes, and treatment
            • More guides
        • Research
          • Research at Dr. Wolff
            Research at Dr. Wolff
            • BioHAP Studies
              BioHAP Studies
              • Benefits of fluoride-free toothpastes with BioHAP
                Benefits of fluoride-free toothpastes with BioHAP
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                © 2026 DR. KURT WOLFF GMBH & CO. KG
                Note

                For the sake of better readability, the simultaneous use of the masculine, feminine, and diverse (m/f/d) gender forms is omitted. All references to persons apply equally to all genders.

                Fluoride MonitorFluoride Monitor: News from science and the press

                FAQFAQ: Answers to your questions

                △ Sudradjat, H., Meyer, F., Fandrich, P. et al. (2024): BDJ Open 10, 7

                DescriptionDescription: Worry-free from the first tooth

                BABY KAREX toothpaste is the ideal introduction to daily tooth brushing for the first little teeth. It cleans gently while effectively protecting against cavities – with "BioHAP" instead of fluoride.

                A hand holds a toothbrush onto which a stripe of toothpaste is being applied.

                Fluoride FactsFluoride Facts: What Is Fluoride?

                Fluoride is a widely distributed mineral that we absorb through food and water. It is not an essential nutrient; while it protects against cavities, an overdose can quickly lead to fluorosis or other health problems.

                Small dried fish, walnuts, and salt on a bright, smooth surface as a symbol of which foods contain fluoride.

                How Do You Absorb Fluoride?

                Fluoride is omnipresent in our daily livesᑎ: toothpaste, tea, fish with bones, fluoridated salt, seafood, mineral water, grain products.

                A scientist in a white lab coat and safety goggles holds a test tube containing white powder, as a symbol of the effects of fluoride on the body.

                What Does Fluoride Do to Your Body?

                A toothbrush and a pea are placed on a bright, smooth surface as a symbol of the fact that fluoride toothpaste should only be applied in a pea-sized or rice grain-sized amount to prevent a fluoride overdose.

                Why Is the Correct Dosage Important?

                A girl looks questioningly into the camera and holds a toothbrush in her hand, as a symbol of the risk-free use of a toothpaste with BioHAP instead of fluoride

                PreventionPrevention: Without Fluoride – Without Risk

                The addition of fluoride in toothpaste is particularly controversial for children under 6 years of age. Children in particular swallow a large portion of their toothpaste.

                Risk-free dosage

                The uncontrollable swallowing of fluoride toothpaste can be particularly harmful to children. Therefore, the common recommendation is to use a rice grain-sized amount of toothpaste.

                An overdose can cause fluorosis.

                With KAREX, swallowing toothpaste is no longer a risk. Swallowing the active ingredient BioHAP is completely safe and without risk.

                Two girls with healthy teeth; the girl on the left is smiling into the camera; the girl on the right is brushing her teeth with a toothbrush and a fluoride-free toothpaste with BioHAP

                Fluorosis Risk

                • Clinical studyClinical study: 39.3 %

                  of parents are not informed about the conditions of use and warnings of fluoride toothpastes.

                  The study shows that parents overdose fluoride-containing toothpastes. This leads to increased fluoride intake, which can result in fluorosis.△

                • Further studies & research findings

                A hand holds a tube of BABY KAREX Toothpaste with the inscription "Toothpaste with BioHAP - fluoride-free"

                ApplicationApplication: For morning, noon & evening

                • KAREX is the all-in-one toothpaste for clean and well-cared-for teeth
                • Application is easy as can be and suitable for all toothbrushes
                • Also for children who cannot yet spit properly
                A hand holds a tube of Baby KAREX and applies a strip of toothpaste to a baby toothbrush to illustrate the application of the toothpaste

                Frequency & Duration

                Brushing teeth with KAREX Toothpaste:

                • 2 x daily for at least 2 minutes
                • Use in the morning and evening & if needed at noon after the meal
                • Re-brushing by an adult is recommended until your child has mastered the brushing technique
                A mother has her baby on her lap; the baby puts a tube of fluoride-free BABY KAREX Baby Toothpaste in its mouth to illustrate that BABY KAREX is safe if swallowed

                Toothpaste swallowed? No worries!

                A blue toothbrush lies on a light, smooth surface; in the background, white Hydroxyapatite in powder form is visible; as a symbol of the fact that KAREX Toothpaste contains only necessary ingredients and no titanium dioxide or sodium lauryl sulfate

                Only as many ingredients as necessary

                More Products

                • Effective cavity protection

                • Flavor-free – mild and pleasant taste

                • Only the most essential ingredients – without fluoride and surfactants

                • Illustration of a tooth in which the tooth crown is represented by a strip of fluoride-free toothpaste with BioHAP

                  Active ingredientActive ingredient: BioHAP – the protective shield for teeth

                  • Bio for biomimetics (imitating nature) and
                  • HAP for Hydroxyapatite (the main component of our teeth and bones).
                • Illustration of a tooth in which the tooth crown is represented by a strip of fluoride-free toothpaste with BioHAP; a blue protective layer and blue hexagons surround the tooth, symbolizing BioHAP’s ability to repair the enamel

                  Remineralization

                  BioHAP repairs the enamel and remineralizes small lesions evenly down into the underlying layers of the tooth.
                  In this way, BioHAP also protects against the development of new cavities.

                • Illustration of a tooth in which the tooth crown is represented by a strip of fluoride-free toothpaste with BioHAP; a blue protective layer surrounds the tooth, symbolizing BioHAP’s ability to protect the enamel from acid attacks

                  Protective layer

                  The microcrystalline structure of BioHAP forms a protective layer on the tooth surface during dental care.
                  Acids and bacteria cannot attack the enamel directly.

                • Illustration of a tooth in which the tooth crown is represented by a strip of fluoride-free toothpaste with BioHAP; a blue protective layer surrounds the tooth and calcium is indicated by blue squares labeled “Ca,” symbolizing BioHAP’s ability to release calcium and thus neutralize the acidic pH value in the oral cavity

                  Acid protection

                • Illustration of a tooth in which the tooth crown is represented by a strip of fluoride-free toothpaste with BioHAP; a blue protective layer surrounds the tooth, keeping bacteria away, symbolizing BioHAP’s effective protection against cavities

                  Biofilm control

                JUNIOR KAREX toothpaste
              • KAREX toothpaste
              • KAREX tooth protection gel
              • Doses of fluoride toothpaste for children up to 24 months.
                • Higher fluoride levels could lower children’s IQ
                • US court calls for stricter drinking water regulation
                • Critics emphasize data uncertainties and the dental health benefits
                • Reduce fluoride intake during pregnancy

                Original article: www.focus.de

                • Kennedy’s influence: As health secretary, Robert F. Kennedy Jr. is strengthening the anti-fluoride movement.
                • Court ruling: A federal judge views fluoride in drinking water as a risk to children’s intelligence.
                • Public opinion: Growing skepticism toward fluoridation due to health concerns.
                • Debate: Fluoridation has historically been seen as a success, but there is now increased discussion about its risks.
                • Health risks: Concern about negative effects on cognitive development.

                Original article: www.nytimes.com

                • Kennedy’s influence: Newly appointed health secretary is addressing water fluoridation in the U.S.
                • Fluoridated drinking water: 72% of the U.S. population receive fluoridated drinking water.
                • WHO warning: Long-term exposure to fluoride concentrations above 1.5 mg/L can cause health problems.
                • Cavity protection with risks: Increased fluoride exposure can cause dental enamel fluorosis and skeletal fluorosis.
                • Fluoride during pregnancy: High fluoride exposure during pregnancy may be associated with neurological problems in children.

                Original article: edition.cnn.com

                • Fluoridated drinking water: link between high fluoride exposure in drinking water and lower IQ scores in children
                • Low IQ in children: the National Toxicology Program shows that water with more than 1.5 mg/L fluoride is associated with lower IQs in children
                • Dental disease fluorosis: US authorities want to minimize risks such as the dental disease fluorosis, which is caused by too much fluoride
                • Protection of the population: the report raises questions about how people can be protected from high fluoride levels
                • Fluoride during pregnancy: pregnant women are advised to reduce their fluoride intake, as fluoride is associated with potential risks to brain development

                Original article: www.theguardian.com

                • IQ report: Fluoride in drinking water can lower children’s IQ.
                • Limits: Problematic from 1.5 mg/L; 0.7 mg/L recommended.
                • Fluoridation: Used since the 1950s for cavity prevention.
                • Natural levels: 0.6% of the U.S. population have water with ≥1.5 mg/L fluoride.
                • 2015 recommendation: Levels lowered to prevent fluorosis.

                Original article: www.newsweek.com

                The use of fluoride in toothpaste is particularly controversial for children under 6 years of age. Children in particular swallow a large portion of the toothpaste.

                Due to the intake of additional sources of fluoride (vitamin D supplements with fluoride, fluoridated salt, etc.), the risk of developing fluorosis (white spots on the teeth caused by increased fluoride intake) increases significantly. For example, the German Federal Institute for Risk Assessment points out that if a children’s toothpaste with 500 ppm fluoride is swallowed, just as much fluoride is ingested as, for instance, through fluoridated salt.

                According to the new recommendations, the amount of swallowed fluoride can therefore double. The risk of fluorosis is significantly higher with toothpastes that have a higher fluoride content (from 1000 ppm).

                KAREX relies on the tooth-related active ingredient Hydroxyapatite (BioHAP) in all products. When swallowed, it is simply dissolved in the stomach. Numerous studies confirm its effectiveness: Hydroxyapatite repairs enamel with every brushing, reduces bacterial adhesion, and thus provides effective protection against cavities.

                Our tooth enamel consists almost entirely of Hydroxyapatite. That is why BioHAP (biomimetic Hydroxyapatite) is used as an active ingredient in oral care. The highly concentrated active ingredient also serves as a source of calcium and protects our teeth against bacterial acids. Numerous studies confirm the benefits of Hydroxyapatite in the field of oral care and prevention.

                Numerous publications confirm the effectiveness of BioHAP in dental care. These include not only laboratory studies (in vitro) but also studies with test specimens under oral cavity conditions (in situ), as well as, in particular, clinical studies on patients (in vivo).
                For more information, feel free to read the German short summary or the original study. You can get an overview of the large number of studies on Hydroxyapatite as an active ingredient in dental care by browsing our study database (usable without registration).

                Effective cavity protection is important from the very first tooth. However, babies and toddlers swallow almost all of the toothpaste while brushing, as they are not yet able to spit at that age.

                BABY KAREX Toothpaste is the ideal introduction to daily toothbrushing. From the first tooth, it gently cleans and at the same time provides effective protection against cavities – with BioHAP, without fluoride.

                The BABY KAREX formula contains only the most essential ingredients and completely avoids fluoride, surfactants, and flavorings, and is harmless if swallowed.

                BABY KAREX Toothpaste can be used without hesitation from the very first tooth. It contains only the most essential ingredients, is completely free from fluoride, surfactants, and flavorings, and is therefore harmless even if swallowed.
                BABY KAREX provides effective protection against cavities while being fluoride-free. Therefore, unlike other children's toothpastes, it is not subject to any dosage restrictions, which makes the daily toothbrushing routine with your child easier.

                BABY KAREX Toothpaste has been specially developed as an introduction to the toothbrushing routine. From the very first tooth, it gently cleans and at the same time provides effective protection against cavities – with BioHAP and without fluoride. In addition, the BABY KAREX formula contains only the most essential ingredients and completely avoids surfactants and flavorings in order to protect the sensitive oral cavity of the little ones. The taste is pleasantly mild and tailored to babies’ flavor preferences. We recommend BABY KAREX Toothpaste for ages 0–2 years.

                KINDER KAREX Toothpaste has been developed for the care of sensitive milk teeth. It offers effective cavity protection with BioHAP, without fluoride. KINDER KAREX remineralizes the teeth and minimizes bacterial adhesion. The fluoride-free formula reduces the risk of fluorosis. The mild flavor is popular with children. We recommend KINDER KAREX Toothpaste up to 6 years of age as a follow-up product to BABY KAREX. However, it can also be used without hesitation for babies from 0 years of age.

                The use of fluoride in toothpaste is particularly controversial for children under 6 years of age. Children in particular swallow a large portion of the toothpaste. Due to the intake of additional sources of fluoride (vitamin D supplements with fluoride, fluoridated salt, etc.), the risk of fluorosis (discoloration of the teeth caused by increased fluoride intake) increases significantly. For example, the German Federal Institute for Risk Assessment points out that if a children’s toothpaste with 500 ppm fluoride is swallowed, just as much fluoride is ingested as, for instance, through fluoridated salt. According to the new recommendations, the amount of swallowed fluoride can therefore double. The risk of fluorosis is significantly higher with toothpastes that have a higher fluoride content (from 1000 ppm).

                BABY KAREX Toothpaste relies on the tooth-related active ingredient Hydroxyapatite. When swallowed, it is simply dissolved in the stomach.
                Numerous studies confirm its effectiveness: Hydroxyapatite repairs enamel with every brushing, reduces bacterial adhesion, and thus provides effective protection against cavities.

                To the general FAQs

                Since 2015, the U.S. National Toxicology Program (NTP) has been investigating the effects of fluoride on neurotoxicity and endocrine disruption. The brain responds sensitively at 1–2 mg/l, the thyroid gland at 2–4 mg/l.ᑎ

                The correct toothpaste dosage not only protects against cavities but also prevents fluoride overdose. The official recommendation for fluoride toothpaste is: pea-sized. Studies show that parents use significantly more toothpaste.ᐳ

                Fluoroses are unsightly white spots on the teeth that are caused by excessive fluoride intake and remain for a lifetime.

                While most children's toothpastes contain fluoride, KAREX toothpaste offers a modern alternative with BioHAP. This nature-inspired active ingredient works without fluoride and reduces the risk of fluorosis.

                Especially young children cannot yet spit out toothpaste properly. Since KAREX Toothpastes are fluoride-free, there is no increased risk of fluorosis even if swallowed.

                The active ingredient BioHAP is simply dissolved in the stomach and is safe even if swallowed.

                Furthermore, special care was taken during the development of our toothpaste to use only necessary ingredients. Therefore, we deliberately avoid the use of sodium lauryl sulfate and titanium dioxide, for example.

                During bacterial acid attacks, BioHAP releases calcium, which maintains the healthy mineralization of the enamel and reduces the tooth-damaging acidic pH value in the oral cavity.

                The bacteria in the oral cavity are bound by BioHAP and prevented from forming a biofilm on the teeth – but not killed.
                In this way, BioHAP helps to keep the oral flora in its natural balance.

                Discover all studies
                Zwei Tuben KINDER KAREX Zahnpasta, Aufschrift: „Zahnpasta mit BioHAP ohne Fluorid. Biomimetischer Hydroxylapatit“.

                KINDER KAREX toothpaste

                2-pack

                5 / 5 (1)
                €8.98100 ml (€89.80 / 1 l) • incl. VAT, plus shipping
                Zwei Tuben KAREX Zahnschutzgel, Aufschrift: „Zahnschutzgel mit BioHAP ohne Fluorid. Biomimetischer Hydroxylapatit“.

                KAREX tooth protection gel

                2-pack

                5 / 5 (12)
                €17.98100 ml (€179.80 / 1 l) • incl. VAT, plus shipping