Cavity and gum protection. With BioHAP instead of fluoride
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For the sake of better readability, the simultaneous use of the masculine, feminine, and diverse (m/f/d) gender forms is omitted. All references to persons apply equally to all genders.
The use of fluoride in toothpaste is particularly controversial for children under 6 years of age. Children in particular swallow a large portion of the toothpaste.
Due to the intake of additional sources of fluoride (vitamin D supplements with fluoride, fluoridated salt, etc.), the risk of developing fluorosis (white spots on the teeth caused by increased fluoride intake) increases significantly. For example, the German Federal Institute for Risk Assessment points out that if a children’s toothpaste with 500 ppm fluoride is swallowed, just as much fluoride is ingested as, for instance, through fluoridated salt.
According to the new recommendations, the amount of swallowed fluoride can therefore double. The risk of fluorosis is significantly higher with toothpastes that have a higher fluoride content (from 1000 ppm).
KAREX relies on the tooth-related active ingredient Hydroxyapatite (BioHAP) in all products. When swallowed, it is simply dissolved in the stomach. Numerous studies confirm its effectiveness: Hydroxyapatite repairs enamel with every brushing, reduces bacterial adhesion, and thus provides effective protection against cavities.
Our tooth enamel consists almost entirely of Hydroxyapatite. That is why BioHAP (biomimetic Hydroxyapatite) is used as an active ingredient in oral care. The highly concentrated active ingredient also serves as a source of calcium and protects our teeth against bacterial acids. Numerous studies confirm the benefits of Hydroxyapatite in the field of oral care and prevention.
Numerous publications confirm the effectiveness of BioHAP in dental care. These include not only laboratory studies (in vitro) but also studies with test specimens under oral cavity conditions (in situ), as well as, in particular, clinical studies on patients (in vivo).
For more information, feel free to read the German short summary or the original study. You can get an overview of the large number of studies on Hydroxyapatite as an active ingredient in dental care by browsing (usable without registration).
ᔭ Schlagenhauf, U. et al. (2019) J. Invest. Clin. Dent. 10, e12399
▲ Limeback, H., Enax, J. & Meyer, F. (2021): Can J Dent Hyg. 2021 Oct 1;55(3):148–159.
◓ Amaechi, B.T., AbdulAzees, P.A., Okoye, L.O. et al. (2020) BDJ Open 6, 98-159
△ Sudradjat, H., Meyer, F., Fandrich, P. et al. (2024): BDJ Open 10, 7
The new KAREX toothpaste is the most advanced solution for healthy teeth and gums. It effectively protects our teeth against cavities and gum problems – without fluoride.
Fluoride is a widely distributed mineral that we absorb through food and water. It is not an essential nutrient; while it protects against cavities, an overdose can quickly lead to fluorosis or other health problems.
Fluoride is omnipresent in our daily livesᑎ: toothpaste, tea, fish with bones, fluoridated salt, seafood, mineral water, grain products.
The addition of fluoride in toothpaste is particularly controversial for children under 6 years of age. Children in particular swallow a large portion of their toothpaste.
The uncontrollable swallowing of fluoride toothpaste can be particularly harmful to children. Therefore, the common recommendation is to use a rice grain-sized amount of toothpaste.
An overdose can cause fluorosis.
With KAREX, swallowing toothpaste is no longer a risk. Swallowing the active ingredient BioHAP is completely safe and without risk.
Effective cavity protection with BioHAP (biomimetic Hydroxyapatite)
Strengthens tooth enamel
Remineralizes teeth and minimizes bacterial buildup
Fresh mint flavor
BioHAP repairs the enamel and remineralizes small lesions evenly down into the underlying layers of the tooth.
In this way, BioHAP also protects against the development of new cavities.
The microcrystalline structure of BioHAP forms a protective layer on the tooth surface during dental care.
Acids and bacteria cannot attack the enamel directly.
Original article: www.focus.de
Original article: www.nytimes.com
Original article: edition.cnn.com
Original article: www.theguardian.com
Original article: www.newsweek.com
Since 2015, the U.S. National Toxicology Program (NTP) has been investigating the effects of fluoride on neurotoxicity and endocrine disruption. The brain responds sensitively at 1–2 mg/l, the thyroid gland at 2–4 mg/l.ᑎ
The correct toothpaste dosage not only protects against cavities but also prevents fluoride overdose. The official recommendation for fluoride toothpaste is: pea-sized. Studies show that parents use significantly more toothpaste.ᐳ
Fluoroses are unsightly white spots on the teeth that are caused by excessive fluoride intake and remain for a lifetime.
While most children's toothpastes contain fluoride, KAREX toothpaste offers a modern alternative with BioHAP. This nature-inspired active ingredient works without fluoride and reduces the risk of fluorosis.
During bacterial acid attacks, BioHAP releases calcium, which maintains the healthy mineralization of the enamel and reduces the tooth-damaging acidic pH value in the oral cavity.
The bacteria in the oral cavity are bound by BioHAP and prevented from forming a biofilm on the teeth – but not killed.
In this way, BioHAP helps to keep the oral flora in its natural balance.
