Hydroxyapatite - an established active substance in modern oral care

The renowned dental book "Toothpastes" summarises various interesting studies and findings about hydroxyapatite in oral care.

Hydroxyapatite has been used and tested in oral care products in Germany since the 1980s. In Asian countries, this substance inspired by nature has been used since the 1980s. A clinical study was able to prove the efficacy in treating caries. It is also said that hydroxyapatite can remineralise initial carious lesions. The biomimetic active substance can be used in both toothpastes and mouthwashes and has also proven particularly effective in repairing initial lesions.

The mechanism is described as follows:

  1.  Hydroxyapatite builds up on the surface of enamel.
  2.  Once it builds up, it penetrates the enamel up to the initial lesion and fills in the smallest defects in the enamel.
  3.  Remineralisation is achieved by hydroxyapatite being deposited on the natural enamel structure.


The publication of the study can be found here.

Source: Loveren, C. v. Toothpastes. Vol. 23 (Karger, 2013)